RESUMO
This Commentary article reviews the history of veterinary immunology in Australia from the 1980s and discusses the key people and areas of research during this period.
Assuntos
Alergia e Imunologia , Medicina Veterinária , Austrália , Medicina Veterinária/história , Alergia e Imunologia/história , História do Século XXRESUMO
In this article, we describe the development of the plant immunity field, starting with efforts to understand the genetic basis for disease resistance, which â¼30 y ago led to the discovery of diverse classes of immune receptors that recognize and respond to infectious microbes. We focus on knowledge gained from studies of the rice XA21 immune receptor that recognizes RaxX (required for activation of XA21 mediated immunity X), a sulfated microbial peptide secreted by the gram-negative bacterium Xanthomonas oryzae pv. oryzae. XA21 is representative of a large class of plant and animal immune receptors that recognize and respond to conserved microbial molecules. We highlight the complexity of this large class of receptors in plants, discuss a possible role for RaxX in Xanthomonas biology, and draw attention to the important role of sulfotyrosine in mediating receptor-ligand interactions.
Assuntos
Resistência à Doença/imunologia , Oryza/imunologia , Proteínas de Plantas/imunologia , Proteínas Serina-Treonina Quinases/imunologia , Agricultura/história , Alergia e Imunologia/história , Alergia e Imunologia/tendências , Infecções Bacterianas/genética , Proteínas de Bactérias/genética , Resistência à Doença/genética , História do Século XIX , História do Século XX , História do Século XXI , Peptídeos/química , Doenças das Plantas/microbiologia , Imunidade Vegetal/imunologia , Proteínas de Plantas/genética , Proteínas de Plantas/metabolismo , Proteínas Serina-Treonina Quinases/genética , Proteínas Serina-Treonina Quinases/metabolismoRESUMO
This article honors the memory of Nilabh Shastri by recounting the messages sent to him by his friend and colleagues. In addition to his obvious gifts as a scientist, he was a treasured mentor, colleague and friend who enriched the lives of those he touched.
Assuntos
Alergia e Imunologia/história , Tutoria , Estudantes , História do Século XX , História do Século XXI , HumanosRESUMO
Bo Zhong studies the regulation of the antiviral innate immunity, inflammation, and tumorigenesis by the protein ubiquitination system.
Assuntos
Alergia e Imunologia/história , Imunidade Inata , Ubiquitinação , Virologia/história , Animais , China , História do Século XXI , Interações Hospedeiro-Patógeno , HumanosRESUMO
The Collegium Internationale Allergologicum (CIA) was founded on 15 October 1954 in London by a group of 48 international allergists and immunologists from 18 countries of all continents, among them such distinguished scientists as Carl Prausnitz-Giles, Sir Henry Dale, Paul Kallos, and many others. Contrary to other international associations in the field, this Collegium limited the number of members in order to allow more intense and open discussions in "the humble spirit of scientific enquiry, friendly cooperation, good fellowship and professional relationships in the field of allergy" as stated in the statutes. It is not possible to apply for membership, and one has to be proposed by at least 2 CIA members and invited to present at least once at a symposium. Over the decades, a rhythm of biannual symposia developed, the 32nd held in Palma de Mallorca in October 2018. These symposia went around the world from London, Rome, Copenhagen, New Orleans, Puerto Vallarta, Nantucket, Hakone, Konstanz, Goeteborg, and Sorrento, just to name a few places. Preferably they were held on islands such as Capri, Corfu, Martinique, Curacao, Bornholm, Malta, and Ischia in order to make it more difficult for people to arrive late or leave early. It is expected that participants stay over the whole length of the 5-day symposium. On these symposia, it is good custom to also present unpublished data, so participants get the latest news. The most important developments in the field of Allergy and Clinical Immunology have been discussed at early stage and sometimes by speakers who later won the Nobel Prize. While all presentations are equal, be it oral communications or posters, there are 3 special lectures, namely the Carl Prausnitz lecture, the Paul Kallos lecture, and a "Relaxing from Immunology" lecture which can be devoted to any interesting topic not necessarily related to medicine or allergy. Since many years, the contents of the symposium are published in a proceedings volume, over a longtime printed within the "International Archives of Allergy and Immunology" which until now is the official journal of the Collegium. Participants agree that in the flood of more and more scientific congresses and larger events, the CIA Symposia are unique in their openness and friendly scientific interchange.
